Pub. Date : 2017 Aug 1
PMID : 28745354
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Soybean isoflavones ameliorate ischemic cardiomyopathy by activating Nrf2-mediated antioxidant responses. | Isoflavones | NFE2 like bZIP transcription factor 2 | Homo sapiens |
2 | Furthermore, isoflavone therapy caused a significant increase in the levels of erythroid-derived 2-like 2 (Nrf2), superoxide dismutase (SOD) and a significant decrease in serum levels of C-reactive protein, 8-isoprostane, malondialdehyde, interleukin-6 and tumor necrosis factor alpha. | Isoflavones | NFE2 like bZIP transcription factor 2 | Homo sapiens |
3 | These results suggest that soybean isoflavones ameliorate IC patients by improving their antioxidant capacities via the upregulation of Nrf2. | Isoflavones | NFE2 like bZIP transcription factor 2 | Homo sapiens |