Title : Soybean isoflavones ameliorate ischemic cardiomyopathy by activating Nrf2-mediated antioxidant responses.

Pub. Date : 2017 Aug 1

PMID : 28745354






3 Functional Relationships(s)
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1 Soybean isoflavones ameliorate ischemic cardiomyopathy by activating Nrf2-mediated antioxidant responses. Isoflavones NFE2 like bZIP transcription factor 2 Homo sapiens
2 Furthermore, isoflavone therapy caused a significant increase in the levels of erythroid-derived 2-like 2 (Nrf2), superoxide dismutase (SOD) and a significant decrease in serum levels of C-reactive protein, 8-isoprostane, malondialdehyde, interleukin-6 and tumor necrosis factor alpha. Isoflavones NFE2 like bZIP transcription factor 2 Homo sapiens
3 These results suggest that soybean isoflavones ameliorate IC patients by improving their antioxidant capacities via the upregulation of Nrf2. Isoflavones NFE2 like bZIP transcription factor 2 Homo sapiens