Title : Differential Requirements for Src-Family Kinases in SYK or ZAP70-Mediated SLP-76 Phosphorylation in Lymphocytes.

Pub. Date : 2017

PMID : 28736554






1 Functional Relationships(s)
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1 In a synthetic biology approach using Schneider (S2) cells, we show that SLP-76 is directly phosphorylated at tyrosines Y113 and Y128 by SYK in the presence of ITAM-containing adapters such as CD3zeta, DAP12, or FcepsilonRgamma. Tyrosine spleen associated tyrosine kinase Homo sapiens