Title : Endocannabinoids exert CB1 receptor-mediated neuroprotective effects in models of neuronal damage induced by HIV-1 Tat protein.

Pub. Date : 2017 Sep

PMID : 28733129






1 Functional Relationships(s)
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1 The direct application of AEA and 2-AG reduced excitotoxic levels of intracellular calcium and promoted neuronal survival following Tat exposure, which was prevented by the CB1R antagonist rimonabant, but not by the CB2R antagonist AM630. glyceryl 2-arachidonate cannabinoid receptor 1 Homo sapiens