Title : Cholesterol 25-Hydroxylase Inhibits Porcine Reproductive and Respiratory Syndrome Virus Replication through Enzyme Activity-Dependent and -Independent Mechanisms.

Pub. Date : 2017 Oct 1

PMID : 28724759






4 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 Cholesterol 25-hydroxylase (CH25H) has recently been identified as a host restriction factor that exerts antiviral effects by catalyzing the production of 25-hydroxycholesterol (25HC). 25-hydroxycholesterol cholesterol 25-hydroxylase Homo sapiens
2 Cholesterol 25-hydroxylase (CH25H) has recently been identified as a host restriction factor that exerts antiviral effects by catalyzing the production of 25-hydroxycholesterol (25HC). 25-hydroxycholesterol cholesterol 25-hydroxylase Homo sapiens
3 CH25H exerts its anti-PRRSV effect not only via the production of 25HC to inhibit viral penetration but also by degrading viral protein through the ubiquitin-proteasome pathway, suggesting that CH25H is a candidate for the development of antiviral therapeutics. 25-hydroxycholesterol cholesterol 25-hydroxylase Homo sapiens
4 CH25H exerts its anti-PRRSV effect not only via the production of 25HC to inhibit viral penetration but also by degrading viral protein through the ubiquitin-proteasome pathway, suggesting that CH25H is a candidate for the development of antiviral therapeutics. 25-hydroxycholesterol cholesterol 25-hydroxylase Homo sapiens