Title : TPL2 (Therapeutic Targeting Tumor Progression Locus-2)/ATF4 (Activating Transcription Factor-4)/SDF1α (Chemokine Stromal Cell-Derived Factor-α) Axis Suppresses Diabetic Retinopathy.

Pub. Date : 2017 Sep 1

PMID : 28724746






1 Functional Relationships(s)
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1 CONCLUSIONS: This study demonstrates that inhibiting the Nepsilon-(carboxymethyl)lysine-induced TPL2/ATF4/SDF1alpha axis can effectively prevent diabetes mellitus-mediated retinal microvascular dysfunction. N(6)-carboxymethyllysine activating transcription factor 4 Homo sapiens