Title : Lycopene Inhibits Metastasis of Human Liver Adenocarcinoma SK-Hep-1 Cells by Downregulation of NADPH Oxidase 4 Protein Expression.

Pub. Date : 2017 Aug 16

PMID : 28723216






1 Functional Relationships(s)
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1 Using transient transfection of siRNA against NOX4, we found that the downregulation of NOX4 could mimic lycopene by inhibiting cell migration and the activities of MMP-9 and MMP-2 during the incubation with or without TGF-beta on SK-Hep-1 cells. Lycopene matrix metallopeptidase 9 Homo sapiens