Title : Bisphenol A (BPA) aggravates multiple low-dose streptozotocin-induced Type 1 diabetes in C57BL/6 mice.

Pub. Date : 2017 Dec

PMID : 28707492






1 Functional Relationships(s)
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1 Low-dose BPA fits a profile of an agent that exhibits pro-diabetogenic effects via T-cell immunomodulation in the early stages of disease development, i.e. decreases in splenic T-cell subpopulations [especially CD4+ T-cells] along with a trend in elevation of splenic T-cell formation of pro-inflammatory cytokines (IFN-gamma, TNF-alpha, and IL-6). bisphenol A interleukin 6 Mus musculus