Pub. Date : 2017 Jun 15
PMID : 28698741
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | AIM: To investigate the association of peroxisome proliferator-activated receptor gamma (PPARG) Pro12Ala polymorphism with polycystic ovary syndrome (PCOS) and its effect on the metabolic parameters in PCOS women. | pro12ala | peroxisome proliferator activated receptor gamma | Homo sapiens |
| 2 | AIM: To investigate the association of peroxisome proliferator-activated receptor gamma (PPARG) Pro12Ala polymorphism with polycystic ovary syndrome (PCOS) and its effect on the metabolic parameters in PCOS women. | pro12ala | peroxisome proliferator activated receptor gamma | Homo sapiens |
| 3 | METHODS: The study used PCR to identify the presence of the PPARG Pro12Ala polymorphism in 100 PCOS women and 120 age-matched healthy women. | pro12ala | peroxisome proliferator activated receptor gamma | Homo sapiens |
| 4 | RESULTS: Significant difference in the genotypes distributions of PPARG Pro12Ala polymorphism was observed among PCOS women and controls (p = 0.03). | pro12ala | peroxisome proliferator activated receptor gamma | Homo sapiens |
| 5 | CONCLUSION: The PPARG Pro12Ala polymorphism might contribute to the risk of PCOS and abnormal metabolic parameters and could be considered as a biomarker for early diagnosis and clinic prediction of metabolic complications. | pro12ala | peroxisome proliferator activated receptor gamma | Homo sapiens |