Pub. Date : 2017 Aug 11
PMID : 28684414
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Kinetic processivity of the two-step oxidations of progesterone and pregnenolone to androgens by human cytochrome P450 17A1. | Progesterone | cytochrome P450 family 17 subfamily A member 1 | Homo sapiens |
| 2 | Cytochrome P450 (P450, CYP) 17A1 plays a critical role in steroid metabolism, catalyzing both the 17alpha-hydroxylation of pregnenolone and progesterone and the subsequent 17alpha,20-lyase reactions to form dehydroepiandrosterone (DHEA) and androstenedione (Andro), respectively, critical for generating glucocorticoids and androgens. | Progesterone | cytochrome P450 family 17 subfamily A member 1 | Homo sapiens |