Title : In vitro phase I metabolism of gamabufotalin and arenobufagin: Reveal the effect of substituent group on metabolic stability.

Pub. Date : 2017 Sep

PMID : 28666968






1 Functional Relationships(s)
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1 This study can provide important data for elucidating the phase I metabolism of GB and AB and can lead to a better understanding of the bufadienolide-CYP3A interaction which is helpful for preclinical development and rational use of bufadienolides. gamabufotalin cytochrome P450 family 3 subfamily A member 4 Homo sapiens