Title : Recognition of a glycosylation substrate by the O-GlcNAc transferase TPR repeats.

Pub. Date : 2017 Jun

PMID : 28659383






3 Functional Relationships(s)
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1 Although a single enzyme, O-GlcNAc transferase (OGT), generates the entire cytosolic O-GlcNAc proteome, it is not understood how it recognizes its protein substrates, targeting only a fraction of serines/threonines in the metazoan proteome for glycosylation. Threonine O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens
2 Although a single enzyme, O-GlcNAc transferase (OGT), generates the entire cytosolic O-GlcNAc proteome, it is not understood how it recognizes its protein substrates, targeting only a fraction of serines/threonines in the metazoan proteome for glycosylation. Threonine O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens
3 Although a single enzyme, O-GlcNAc transferase (OGT), generates the entire cytosolic O-GlcNAc proteome, it is not understood how it recognizes its protein substrates, targeting only a fraction of serines/threonines in the metazoan proteome for glycosylation. Threonine O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens