Title : Synergistic effect of melatonin and ghrelin in preventing cisplatin-induced ovarian damage via regulation of FOXO3a phosphorylation and binding to the p27Kip1 promoter in primordial follicles.

Pub. Date : 2017 Oct

PMID : 28658519






2 Functional Relationships(s)
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1 Synergistic effect of melatonin and ghrelin in preventing cisplatin-induced ovarian damage via regulation of FOXO3a phosphorylation and binding to the p27Kip1 promoter in primordial follicles. Cisplatin cyclin dependent kinase inhibitor 1B Homo sapiens
2 Co-administration of melatonin and ghrelin in cisplatin-treated ovaries restored the expression of p27Kip1 , which is critical for retention of the dormant status of primordial follicles. Cisplatin cyclin dependent kinase inhibitor 1B Homo sapiens