Title : Steroidogenic Metabolism of Galeterone Reveals a Diversity of Biochemical Activities.

Pub. Date : 2017 Jul 20

PMID : 28648378






1 Functional Relationships(s)
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1 Galeterone is a steroidal CYP17A1 inhibitor, androgen receptor (AR) antagonist, and AR degrader, under evaluation in a phase III clinical trial for castration-resistant prostate cancer (CRPC). 3-hydroxy-17-(1H-benzimidazole-1-yl)androsta-5,16-diene cytochrome P450 family 17 subfamily A member 1 Homo sapiens