Pub. Date : 2018 Mar
PMID : 28635037
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cocaine triggers a transient nuclear accumulation of HDAC5 that functions to limit the development of cocaine reward behavior. | Cocaine | histone deacetylase 5 | Homo sapiens |
| 2 | Cocaine triggers a transient nuclear accumulation of HDAC5 that functions to limit the development of cocaine reward behavior. | Cocaine | histone deacetylase 5 | Homo sapiens |
| 3 | In this study, we report that cocaine and cAMP signaling in striatum produced differential phosphorylation and subcellular localization of HDAC4 and HDAC5. | Cocaine | histone deacetylase 5 | Homo sapiens |
| 4 | Together, our findings suggest that, despite high sequence homology, HDAC4 and HDAC5 are oppositely regulated by cocaine-induced signaling in vivo and have distinct roles in regulating cocaine behaviors. | Cocaine | histone deacetylase 5 | Homo sapiens |