Title : Photoaffinity labelling of MSH receptors on Anolis melanophores: effects of catecholamines, calcium and forskolin.

Pub. Date : 1985

PMID : 2860247






5 Functional Relationships(s)
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1 Photoaffinity labelling of MSH receptors on Anolis melanophores: effects of catecholamines, calcium and forskolin. Catecholamines proopiomelanocortin Homo sapiens
2 Photoaffinity labelling of MSH receptors on Anolis melanophores was used as a tool for studying the effects of catecholamines, calcium and forskolin on hormone-receptor interaction and receptor-adenylate cyclase coupling. Catecholamines proopiomelanocortin Homo sapiens
3 Covalent attachment of photoreactive alpha-MSH to its receptor was suppressed in calcium-free buffer but was hardly influenced by catecholamines or forskolin. Catecholamines proopiomelanocortin Homo sapiens
4 The suppression of pigment dispersion by catecholamines was blocked by the simultaneous presence of yohimbine but not prazosin, indicating that the catecholamines antagonize the alpha-MSH signal by inhibitory action on the adenylate cyclase system through an alpha-2 receptor. Catecholamines proopiomelanocortin Homo sapiens
5 The suppression of pigment dispersion by catecholamines was blocked by the simultaneous presence of yohimbine but not prazosin, indicating that the catecholamines antagonize the alpha-MSH signal by inhibitory action on the adenylate cyclase system through an alpha-2 receptor. Catecholamines proopiomelanocortin Homo sapiens