Title : Characteristics of tyrosine hydroxylase activation by K+-induced depolarization and/or forskolin in rat striatal slices.

Pub. Date : 1985 Jul

PMID : 2860207






4 Functional Relationships(s)
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1 The mechanisms of tyrosine hydroxylase (TH) activation by depolarization or exposure of dopaminergic terminals to cyclic AMP have been compared using rat striatal slices. Cyclic AMP tyrosine hydroxylase Rattus norvegicus
2 The mechanisms of tyrosine hydroxylase (TH) activation by depolarization or exposure of dopaminergic terminals to cyclic AMP have been compared using rat striatal slices. Cyclic AMP tyrosine hydroxylase Rattus norvegicus
3 Clear distinction between the two activating processes was further confirmed by the facts that heparin- and cyclic AMP-dependent phosphorylation stimulated TH activity from K+-exposed (and control) tissues but not that from striatal slices incubated with forskolin (or dibutyryl cyclic AMP). Cyclic AMP tyrosine hydroxylase Rattus norvegicus
4 Clear distinction between the two activating processes was further confirmed by the facts that heparin- and cyclic AMP-dependent phosphorylation stimulated TH activity from K+-exposed (and control) tissues but not that from striatal slices incubated with forskolin (or dibutyryl cyclic AMP). Cyclic AMP tyrosine hydroxylase Rattus norvegicus