Title : PTEN, a negative regulator of PI3K/Akt signaling, sustains brain stem cardiovascular regulation during mevinphos intoxication.

Pub. Date : 2017 Sep 1

PMID : 28601397






1 Functional Relationships(s)
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1 Based on the guiding hypothesis that PTEN may sustain brain stem cardiovascular regulation during mevinphos intoxication as a negative regulator of PI3K/Akt signaling in the RVLM, we aimed in this study to clarify the mechanistic role of PTEN in mevinphos-induced circulatory depression. Mevinphos phosphatase and tensin homolog Rattus norvegicus