Title : GRF increases release of growth hormone and arachidonate from anterior pituitary cells.

Pub. Date : 1985 Apr

PMID : 2858979






7 Functional Relationships(s)
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1 GRF increases release of growth hormone and arachidonate from anterior pituitary cells. Arachidonic Acid growth hormone releasing hormone Homo sapiens
2 A study was designed to determine whether arachidonate release from anterior pituitary cells is modified by growth hormone-releasing factor (GRF) or somatostatin (SRIF). Arachidonic Acid growth hormone releasing hormone Homo sapiens
3 A study was designed to determine whether arachidonate release from anterior pituitary cells is modified by growth hormone-releasing factor (GRF) or somatostatin (SRIF). Arachidonic Acid growth hormone releasing hormone Homo sapiens
4 GRF in a concentration-dependent manner (1-30 nM) stimulated growth hormone and arachidonate release, whereas SRIF (100 nM) blocked the GRF-induced increase of growth hormone and arachidonate release. Arachidonic Acid growth hormone releasing hormone Homo sapiens
5 GRF in a concentration-dependent manner (1-30 nM) stimulated growth hormone and arachidonate release, whereas SRIF (100 nM) blocked the GRF-induced increase of growth hormone and arachidonate release. Arachidonic Acid growth hormone releasing hormone Homo sapiens
6 The effects of GRF on growth hormone and arachidonate were evident at time intervals as brief as 5 min. Arachidonic Acid growth hormone releasing hormone Homo sapiens
7 These findings support the hypothesis that arachidonate may play a role in the GRF-induced growth hormone release. Arachidonic Acid growth hormone releasing hormone Homo sapiens