Title : Effect of topical rebamipide on goblet cells in the lid wiper of human conjunctiva.

Pub. Date : 2017 Jun

PMID : 28587435






5 Functional Relationships(s)
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1 The aim of the present study was to analyze the changes in goblet cell number, cell proliferation, and epidermal growth factor receptor (EGFR) induced by topical rebamipide addition to the lid wiper of humans. rebamipide epidermal growth factor receptor Homo sapiens
2 The aim of the present study was to analyze the changes in goblet cell number, cell proliferation, and epidermal growth factor receptor (EGFR) induced by topical rebamipide addition to the lid wiper of humans. rebamipide epidermal growth factor receptor Homo sapiens
3 Immunohistochemistry revealed that EGFR levels in the lid wiper epithelial cells were significantly higher in the rebamipide group compared with the non-rebamipide group (P=0.0237). rebamipide epidermal growth factor receptor Homo sapiens
4 Immunohistochemistry revealed that EGFR levels in the lid wiper epithelial cells were significantly higher in the rebamipide group compared with the non-rebamipide group (P=0.0237). rebamipide epidermal growth factor receptor Homo sapiens
5 These results suggest that topical rebamipide application increases the number of goblet cells in the lid wiper, which in turn upregulates the expression of EGFR. rebamipide epidermal growth factor receptor Homo sapiens