Title : Effects of hypophysiotropic factors on growth hormone and prolactin secretion from somatotroph adenomas in culture.

Pub. Date : 1985 May

PMID : 2858494






3 Functional Relationships(s)
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1 In 8 of 9 somatotroph adenomas that concomitantly secreted PRL, the addition of GHRH likewise increased PRL release. ghrh prolactin Homo sapiens
2 Omission of extracellular Ca2+ blocked the stimulatory effect of GHRH on GH and PRL secretion. ghrh prolactin Homo sapiens
3 When cells were coincubated with 0.1 nM somatostatin, GH and PRL secretion induced by 10 nM GHRH were completely blocked in most adenomas. ghrh prolactin Homo sapiens