Title : Head and neck cancer cell radiosensitization upon dual targeting of c-Abl and beta1-integrin.

Pub. Date : 2017 Sep

PMID : 28578803






1 Functional Relationships(s)
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1 Based on our previous findings indicating c-Abl hyperphosphorylation on tyrosine (Y) 412 and threonine (T) 735 upon beta1-integrin inhibition, we hypothesized c-Abl tyrosine kinase as an important mediator of beta1-integrin signaling for radioresistance. Threonine ABL proto-oncogene 1, non-receptor tyrosine kinase Homo sapiens