Pub. Date : 2017 Sep
PMID : 28578001
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | 1alpha,25-Dihydroxyvitamin D3 enhances TRPV6 transcription through p38 MAPK activation and GADD45 expression. | Calcitriol | mitogen-activated protein kinase 14 | Homo sapiens |
2 | By searching for a signal transduction pathway involved in 1,25(OH)2D3-induced expression of TRPV6, we found that a p38 mitogen-activated protein kinase (MAPK) inhibitor reduces the expression of TRPV6 but not CYP24A1 in 1,25(OH)2D3-treated SW480 cells. | Calcitriol | mitogen-activated protein kinase 14 | Homo sapiens |
3 | By searching for a signal transduction pathway involved in 1,25(OH)2D3-induced expression of TRPV6, we found that a p38 mitogen-activated protein kinase (MAPK) inhibitor reduces the expression of TRPV6 but not CYP24A1 in 1,25(OH)2D3-treated SW480 cells. | Calcitriol | mitogen-activated protein kinase 14 | Homo sapiens |
4 | Knockdown experiments showed that p38alpha is involved in 1,25(OH)2D3-induced expression of TRPV6 but not CYP24A1. | Calcitriol | mitogen-activated protein kinase 14 | Homo sapiens |