Title : Replication-Coupled Dilution of H4K20me2 Guides 53BP1 to Pre-replicative Chromatin.

Pub. Date : 2017 May 30

PMID : 28564601






1 Functional Relationships(s)
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1 The H4K20me2-mediated chromatin association of 53BP1 thus represents an inbuilt mechanism to distinguish DSBs in pre- versus post-replicative chromatin, allowing for localized repair pathway choice decisions based on the availability of replication-generated template strands for HDR. dsbs tumor protein p53 binding protein 1 Homo sapiens