Title : The regioselective glucuronidation of morphine by dimerized human UGT2B7, 1A1, 1A9 and their allelic variants.

Pub. Date : 2017 Aug

PMID : 28552915






2 Functional Relationships(s)
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Compound Name
Protein Name
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1 Uridine diphosphate-glucuronosyltransferase (UGT) 2B7 is expressed mostly in the human liver, lung and kidney and can transfer endogenous glucuronide group into its substrate and impact the pharmacological effects of several drugs such as estriol, AZT and morphine. Glucuronides UDP glucuronosyltransferase family 2 member B7 Homo sapiens
2 The UGT1A9*2-UGT2B7*1 double enzyme has the lowest M3G:M6G ratio, reflecting that more M6G would form in morphine glucuronide metabolism. Glucuronides UDP glucuronosyltransferase family 2 member B7 Homo sapiens