Title : Population pharmacokinetics of carvedilol enantiomers and their metabolites in healthy subjects and type-2 diabetes patients.

Pub. Date : 2017 Nov 15

PMID : 28522373






1 Functional Relationships(s)
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1 Carvedilol, a drug available as a racemic mixture, is metabolised into hydroxyphenylcarvedilol (OHC) by CYP2D6 and O-desmethylcarvedilol (DMC) by CYP2C9 followed by conjugation to glucuronides. hydroxyphenylcarvedilol cytochrome P450 family 2 subfamily D member 6 Homo sapiens