Title : cGMP signaling inhibits platelet shape change through regulation of the RhoA-Rho Kinase-MLC phosphatase signaling pathway.

Pub. Date : 2017 Aug

PMID : 28509344






1 Functional Relationships(s)
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1 Thrombin caused the GTP loading and activation of RhoA, leading to the ROCK-mediated phosphorylation of MLCP on threonine 853 (thr853 ), which is known to inhibit phosphatase activity. Threonine ras homolog family member A Homo sapiens