Pub. Date : 2017 Jun 1
PMID : 28504645
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The pathologic disulfide HMGB1 isoform progressively increased in blood before epilepsy onset and prospectively identified animals that developed the disease. | Disulfides | high mobility group box 1 | Homo sapiens |
| 2 | Consistent with animal data, we observed early expression of disulfide HMGB1 in patients with newly diagnosed epilepsy, and its persistence was associated with subsequent seizures. | Disulfides | high mobility group box 1 | Homo sapiens |
| 3 | In contrast with patients with well-controlled epilepsy, patients with chronic, drug-refractory epilepsy persistently expressed the acetylated, disulfide HMGB1 isoforms. | Disulfides | high mobility group box 1 | Homo sapiens |