Pub. Date : 2017 Aug
PMID : 28501025
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In the AhR assay using a sensitive DR-EcoScreen cell line, five of the 25 PCB congeners showed agonistic activity. | Polychlorinated Biphenyls | aryl hydrocarbon receptor | Homo sapiens |
| 2 | We newly found that PCB-1, -35 and -56 can act as AhR agonists. | Polychlorinated Biphenyls | aryl hydrocarbon receptor | Homo sapiens |
| 3 | These results suggest that unintentional PCBs in pigments and chemical products might act as agonists and/or antagonists against ERalpha/beta, AR, GR, and AhR, and some of the PCBs might disrupt endocrine functions via multiple receptors and/or simultaneously induce dioxin-like activity via AhR. | Polychlorinated Biphenyls | aryl hydrocarbon receptor | Homo sapiens |
| 4 | These results suggest that unintentional PCBs in pigments and chemical products might act as agonists and/or antagonists against ERalpha/beta, AR, GR, and AhR, and some of the PCBs might disrupt endocrine functions via multiple receptors and/or simultaneously induce dioxin-like activity via AhR. | Polychlorinated Biphenyls | aryl hydrocarbon receptor | Homo sapiens |
| 5 | These results suggest that unintentional PCBs in pigments and chemical products might act as agonists and/or antagonists against ERalpha/beta, AR, GR, and AhR, and some of the PCBs might disrupt endocrine functions via multiple receptors and/or simultaneously induce dioxin-like activity via AhR. | Polychlorinated Biphenyls | aryl hydrocarbon receptor | Homo sapiens |