Title : Assessment of the Relation Between SNP in MxA Gene and the Responsiveness of Egyptian HCV Genotype 4 Patients to Pegylated Interferon and Ribavirin Treatment.

Pub. Date : 2017 Apr

PMID : 28496530






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 Treatment with PegIFN stimulates the expression of a number of host genes encoding enzymes with antiviral activities, including myxovirus resistance gene-A (MxA gene). pegifn MX dynamin like GTPase 1 Homo sapiens
2 The aim of the work was to assess the relation between the SNP in the MxA gene and its impact on treatment of chronic HCV patients with PegIFN and ribavirin. pegifn MX dynamin like GTPase 1 Homo sapiens
3 Our results call for additional large studies and/or meta-analysis of all currently available data to examine the role of MxA nt-88 SNP in predicting response to PegIFN and ribavirin in patients with IFN-alpha naive HCV genotype 4. pegifn MX dynamin like GTPase 1 Homo sapiens