Protein Name MX dynamin like GTPase 1
Organism Homo sapiens
Gene ID 4599
Gene Symbol


UniProt P20591 (MX1_HUMAN)
Relationships Total Number of functionally related compound(s) : 158
Total Number of Articles : 174

MX dynamin like GTPase 1

Gene Summary

This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that participates in the cellular antiviral response. The encoded protein is induced by type I and type II interferons and antagonizes the replication process of several different RNA and DNA viruses. There is a related gene located adjacent to this gene on chromosome 21, and there are multiple pseudogenes located in a cluster on chromosome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

  • interferon-induced GTP-binding protein Mx1
  • interferon-induced protein p78
  • interferon-inducible protein p78
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