Title : Combined treatment with Metformin and 2-deoxy glucose induces detachment of viable MDA-MB-231 breast cancer cells in vitro.

Pub. Date : 2017 May 11

PMID : 28496098






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Co-treatment of MDA-MB-231 cells with metformin and 2-DG induced a strong activation of AMP-activated protein kinase (AMPK), which was reduced by AMPK inhibitor compound C that prevented detachment of MDA-MB-231 cells. Deoxyglucose protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens
2 Co-treatment of MDA-MB-231 cells with metformin and 2-DG induced a strong activation of AMP-activated protein kinase (AMPK), which was reduced by AMPK inhibitor compound C that prevented detachment of MDA-MB-231 cells. Deoxyglucose protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens
3 Co-treatment of MDA-MB-231 cells with metformin and 2-DG induced a strong activation of AMP-activated protein kinase (AMPK), which was reduced by AMPK inhibitor compound C that prevented detachment of MDA-MB-231 cells. Deoxyglucose protein kinase AMP-activated catalytic subunit alpha 2 Homo sapiens