Title : Protection of oxidative stress induced apoptosis in osteosarcoma cells by dihydromyricetin through down-regulation of caspase activation and up-regulation of BcL-2.

Pub. Date : 2017 May

PMID : 28490955






3 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Protection of oxidative stress induced apoptosis in osteosarcoma cells by dihydromyricetin through down-regulation of caspase activation and up-regulation of BcL-2. dihydromyricetin BCL2 apoptosis regulator Homo sapiens
2 However, pre-treatment of MG63 cells with 30 muM dose of dihydromyricetin for 48 h significantly prevented hydrogen peroxide induced increase in caspase-3 and -9 levels and reduction in Bcl-2 level. dihydromyricetin BCL2 apoptosis regulator Homo sapiens
3 Thus dihydromyricetin prevents hydrogen peroxide induced reduction in viability and induction of apoptosis in MG63 cells through down-regulation of caspase activation and up-regulation of Bcl-2 levels. dihydromyricetin BCL2 apoptosis regulator Homo sapiens