Pub. Date : 2017 May
PMID : 28490955
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Protection of oxidative stress induced apoptosis in osteosarcoma cells by dihydromyricetin through down-regulation of caspase activation and up-regulation of BcL-2. | dihydromyricetin | BCL2 apoptosis regulator | Homo sapiens |
2 | However, pre-treatment of MG63 cells with 30 muM dose of dihydromyricetin for 48 h significantly prevented hydrogen peroxide induced increase in caspase-3 and -9 levels and reduction in Bcl-2 level. | dihydromyricetin | BCL2 apoptosis regulator | Homo sapiens |
3 | Thus dihydromyricetin prevents hydrogen peroxide induced reduction in viability and induction of apoptosis in MG63 cells through down-regulation of caspase activation and up-regulation of Bcl-2 levels. | dihydromyricetin | BCL2 apoptosis regulator | Homo sapiens |