Pub. Date : 2017 May 10
PMID : 28489026
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Here, the role of tert-butyl hydroperoxide (t-BHP) in redox regulation of PTEN was analyzed by using cell-based and in vitro assays. | tert-Butylhydroperoxide | phosphatase and tensin homolog | Homo sapiens |
| 2 | Exposure to t-BHP led to oxidation of recombinant PTEN. | tert-Butylhydroperoxide | phosphatase and tensin homolog | Homo sapiens |
| 3 | In contrast to H2O2, PTEN oxidation by t-BHP was irreversible in HeLa cells. | tert-Butylhydroperoxide | phosphatase and tensin homolog | Homo sapiens |
| 4 | Taken together, these results indicate that t-BHP induces PTEN oxidation and inhibits Trx system, which results in irreversible PTEN oxidation in HeLa cells. | tert-Butylhydroperoxide | phosphatase and tensin homolog | Homo sapiens |
| 5 | Taken together, these results indicate that t-BHP induces PTEN oxidation and inhibits Trx system, which results in irreversible PTEN oxidation in HeLa cells. | tert-Butylhydroperoxide | phosphatase and tensin homolog | Homo sapiens |