Title : Regulation of miR-483-3p by the O-linked N-acetylglucosamine transferase links chemosensitivity to glucose metabolism in liver cancer cells.

Pub. Date : 2017 May 8

PMID : 28481368






1 Functional Relationships(s)
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1 Here we demonstrate that in HepG2 cells, the molecular link between glucose concentration and miR-483-3p expression entails the O-linked N-acetylglucosamine (O-GlcNAc) transferase (OGT), which stabilizes the transcriptional complex at the miR-483 promoter. o-linked n-acetylglucosamine O-linked N-acetylglucosamine (GlcNAc) transferase Homo sapiens