Title : Octreotide therapy and restricted fetal growth: pregnancy in familial hyperinsulinemic hypoglycemia.

Pub. Date : 2017

PMID : 28458896






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1 LEARNING POINTS: Gain-of-function mutations in GCK cause familial hyperinsulinemic hypoglycemia.Hypoglycemia during pregnancy may have serious health implications for mother and fetus.Pregnancy with hyperinsulinism represents a medical dilemma as hypoglycemia as well as octreotide treatment may pose a risk of fetal growth restriction.In some cases of familial hyperinsulinemic hypoglycemia, blood glucose levels can be successfully managed through diet only. Blood Glucose glucokinase Homo sapiens