Title : Tau peptides and tau mutant protein aggregation inhibition by cationic polyethyleneimine and polyarginine.

Pub. Date : 2017 Sep

PMID : 28456996






2 Functional Relationships(s)
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1 Here, we study the inhibitory potential of a cationic polymer polyethyleneimine (PEI) and a cationic polypeptide arginine (Arg) on the aggregation of VQIVYK, and GKVQIINKLDL peptides, and tau mutant protein (P301L), found frequently in taupathy. Arginine microtubule associated protein tau Homo sapiens
2 Results show that PEI and Arg significantly inhibit tau peptides and protein aggregation. Arginine microtubule associated protein tau Homo sapiens