Title : Pluronic based β-cyclodextrin polyrotaxanes for treatment of Niemann-Pick Type C disease.

Pub. Date : 2017 Apr 28

PMID : 28452365






2 Functional Relationships(s)
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1 To address these shortcomings, we sought to design a family of HP-beta-CD pro-drug delivery vehicles, known as polyrotaxanes (PR), capable of increasing the efficacy of a given injected dose by improving both pharmacokinetic profile and bioavailability of the HP-beta-CD agent. Rotaxanes beta-carotene oxygenase 1 Mus musculus
2 To address these shortcomings, we sought to design a family of HP-beta-CD pro-drug delivery vehicles, known as polyrotaxanes (PR), capable of increasing the efficacy of a given injected dose by improving both pharmacokinetic profile and bioavailability of the HP-beta-CD agent. Rotaxanes beta-carotene oxygenase 1 Mus musculus