Title : Bupivacaine effectively relieves inflammation-induced pain by suppressing activation of the NF-κB signalling pathway and inhibiting the activation of spinal microglia and astrocytes.

Pub. Date : 2017 Mar

PMID : 28450945






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1 Furthermore, reverse transcription-quantitative polymerase chain reaction analysis was performed to analyze the expression levels of inflammatory cytokines, which demonstrated that bupivacaine significantly inhibited the expression of TNF-alpha, IL-1beta and IL-6, as compared with the untreated group (P<0.01). Bupivacaine tumor necrosis factor Rattus norvegicus