Pub. Date : 2017 Jun
PMID : 28415048
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Baicalein increases cisplatin sensitivity of A549 lung adenocarcinoma cells via PI3K/Akt/NF-kappaB pathway. | Cisplatin | nuclear factor kappa B subunit 1 | Homo sapiens |
| 2 | We found that A549/CDDP (resistant to CDDP) cells not only acquired epithelial-mesenchymal transition (EMT) phenotype, but also showed increased NF-kappaB activity compared with A549 cells (sensitive to CDDP). | Cisplatin | nuclear factor kappa B subunit 1 | Homo sapiens |
| 3 | We found that A549/CDDP (resistant to CDDP) cells not only acquired epithelial-mesenchymal transition (EMT) phenotype, but also showed increased NF-kappaB activity compared with A549 cells (sensitive to CDDP). | Cisplatin | nuclear factor kappa B subunit 1 | Homo sapiens |
| 4 | We found that A549/CDDP (resistant to CDDP) cells not only acquired epithelial-mesenchymal transition (EMT) phenotype, but also showed increased NF-kappaB activity compared with A549 cells (sensitive to CDDP). | Cisplatin | nuclear factor kappa B subunit 1 | Homo sapiens |
| 5 | Our study further demonstrated that PI3K/Akt/NF-kappaB pathway controlled CDDP resistance via EMT and NF-kappaB-mediated apoptosis. | Cisplatin | nuclear factor kappa B subunit 1 | Homo sapiens |
| 6 | Our study further demonstrated that PI3K/Akt/NF-kappaB pathway controlled CDDP resistance via EMT and NF-kappaB-mediated apoptosis. | Cisplatin | nuclear factor kappa B subunit 1 | Homo sapiens |