Pub. Date : 2017 Jul
PMID : 28414098
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cytosolic calcium mediates RIP1/RIP3 complex-dependent necroptosis through JNK activation and mitochondrial ROS production in human colon cancer cells. | Calcium | mitogen-activated protein kinase 8 | Homo sapiens |
| 2 | In summary, our study demonstrated that RIP1/RIP3 complex-triggered cytosolic calcium accumulation is a critical mediator in MAM-induced necroptosis through sustained JNK activation and mitochondrial ROS production. | Calcium | mitogen-activated protein kinase 8 | Homo sapiens |