Title : SARS coronavirus papain-like protease up-regulates the collagen expression through non-Samd TGF-β1 signaling.

Pub. Date : 2017 May 2

PMID : 28414040






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Moreover, selective inhibitors TGF-betaRI and STAT6 (AS1517499) ascertained that STAT6 activation was required for PLpro-induced TGF-beta1-dependent up-regulation of Type I collagen in human lung epithelial cells. 4-(benzylamino)-2-((2-(3-chloro-4-hydroxyphenyl)ethyl)amino)pyrimidine-5-carboxamide signal transducer and activator of transcription 6 Homo sapiens
2 Moreover, selective inhibitors TGF-betaRI and STAT6 (AS1517499) ascertained that STAT6 activation was required for PLpro-induced TGF-beta1-dependent up-regulation of Type I collagen in human lung epithelial cells. 4-(benzylamino)-2-((2-(3-chloro-4-hydroxyphenyl)ethyl)amino)pyrimidine-5-carboxamide signal transducer and activator of transcription 6 Homo sapiens