Title : Novel selective β1-adrenoceptor antagonists for concomitant cardiovascular and respiratory disease.

Pub. Date : 2017 Jul

PMID : 28400472






1 Functional Relationships(s)
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1 Radioligand binding studies and functional assays that use human receptors expressed in Chinese hamster ovary cells demonstrate that NDD-713 and -825 have nanomolar beta1-AR affinity >500-fold beta1-AR vs beta2-AR selectivity and no agonism. Nordazepam adrenoceptor beta 2 Homo sapiens