Pub. Date : 2017 Jul 15
PMID : 28396195
8 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Treatment with salvianolic acid B restores endothelial function in angiotensin II-induced hypertensive mice. | salvianolic acid B | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | Mus musculus |
| 2 | The present study examined the vasoprotective effect of Sal B in hypertensive mice induced by angiotensin II (Ang II). | salvianolic acid B | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | Mus musculus |
| 3 | The present study examined the vasoprotective effect of Sal B in hypertensive mice induced by angiotensin II (Ang II). | salvianolic acid B | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | Mus musculus |
| 4 | Sal B (25mg/kg/day) was administered via oral gavage for 11days to Ang II (1.2mg/kg/day)-infused C57BL/6J mice (8-10weeks old). | salvianolic acid B | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | Mus musculus |
| 5 | Oral administration of Sal B reversed the Ang II-induced elevation of arterial systolic blood pressure in mice, augmented the impaired endothelium-dependent relaxations and attenuated the exaggerated endothelium-dependent contractions in both aortas and renal arteries of Ang II-infused mice. | salvianolic acid B | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | Mus musculus |
| 6 | Oral administration of Sal B reversed the Ang II-induced elevation of arterial systolic blood pressure in mice, augmented the impaired endothelium-dependent relaxations and attenuated the exaggerated endothelium-dependent contractions in both aortas and renal arteries of Ang II-infused mice. | salvianolic acid B | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | Mus musculus |
| 7 | In addition, Sal B treatment normalized the elevated levels of AT1 receptors, NADPH oxidase subunits (NOx-2 and NOx-4) and nitrotyrosine in arteries of Ang II-infused mice or in Ang II-treated HUVECs. | salvianolic acid B | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | Mus musculus |
| 8 | In addition, Sal B treatment normalized the elevated levels of AT1 receptors, NADPH oxidase subunits (NOx-2 and NOx-4) and nitrotyrosine in arteries of Ang II-infused mice or in Ang II-treated HUVECs. | salvianolic acid B | angiotensinogen (serpin peptidase inhibitor, clade A, member 8) | Mus musculus |