Title : Cellular and molecular effects of recombinant interferon gamma in chronic granulomatous disease.

Pub. Date : 1988 Jun

PMID : 2839459






2 Functional Relationships(s)
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1 We have examined the potential of IFN-gamma to ameliorate the physiologic defect of CGD by studying its effects on CGD phagocyte superoxide generation, NADPH-oxidase kinetics, and expression of the gene for the phagocyte cytochrome b heavy chain. Superoxides interferon gamma Homo sapiens
2 All subjects whose phagocytes had responded in vitro showed complete or partial correction of the CGD defect in superoxide generation for up to 1 month after IFN-gamma administration. Superoxides interferon gamma Homo sapiens