Title : Folate cycle enzyme MTHFD1L confers metabolic advantages in hepatocellular carcinoma.

Pub. Date : 2017 May 1

PMID : 28394261






4 Functional Relationships(s)
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1 Folate cycle enzyme MTHFD1L confers metabolic advantages in hepatocellular carcinoma. Folic Acid methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like Homo sapiens
2 We found that an enzyme in the folate cycle, methylenetetrahydrofolate dehydrogenase 1-like (MTHFD1L), plays an essential role in support of cancer growth. Folic Acid methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like Homo sapiens
3 We found that an enzyme in the folate cycle, methylenetetrahydrofolate dehydrogenase 1-like (MTHFD1L), plays an essential role in support of cancer growth. Folic Acid methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like Homo sapiens
4 Taken together, our study identifies MTHFD1L in the folate cycle as an important metabolic pathway in cancer cells with the potential for therapeutic targeting. Folic Acid methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like Homo sapiens