Title : New hybrid molecules combining benzothiophene or benzofuran with rhodanine as dual COX-1/2 and 5-LOX inhibitors: Synthesis, biological evaluation and docking study.

Pub. Date : 2017 Jun

PMID : 28390993






1 Functional Relationships(s)
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1 New molecular hybrids combining benzothiophene or its bioisostere benzofuran with rhodanine were synthesized as potential dual COX-2/5-LOX inhibitors. benzofuran arachidonate 5-lipoxygenase Homo sapiens