Title : Mechanism of Cytochrome P450 17A1-Catalyzed Hydroxylase and Lyase Reactions.

Pub. Date : 2017 May 22

PMID : 28387522






2 Functional Relationships(s)
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Protein Name
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1 Cytochrome P450 17A1 (CYP17A1) catalyzes C17 hydroxylation of pregnenolone and progesterone and the subsequent C17-C20 bond cleavage (lyase reaction) to form androgen precursors. Pregnenolone cytochrome P450 family 17 subfamily A member 1 Homo sapiens
2 Cytochrome P450 17A1 (CYP17A1) catalyzes C17 hydroxylation of pregnenolone and progesterone and the subsequent C17-C20 bond cleavage (lyase reaction) to form androgen precursors. Pregnenolone cytochrome P450 family 17 subfamily A member 1 Homo sapiens