Title : Inhibition of β-Secretase Activity by Monoterpenes, Sesquiterpenes, and C13 Norisoprenoids.

Pub. Date : 2017 Aug 1

PMID : 28381772






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 The results showed that the most potent inhibitor of BACE1 was geranyl acetone followed by (+)-camphor, (-)-fenchone, (+)-fenchone, and (-)-camphor with the half-maximal inhibitory concentration (IC50) values of 51.9 +- 3.9, 95.9 +- 11.0, 106.3 +- 14.9, 117.0 +- 18.6, and 134.1 +- 16.4 muM, respectively. Camphor beta-secretase 1 Homo sapiens
2 The results showed that the most potent inhibitor of BACE1 was geranyl acetone followed by (+)-camphor, (-)-fenchone, (+)-fenchone, and (-)-camphor with the half-maximal inhibitory concentration (IC50) values of 51.9 +- 3.9, 95.9 +- 11.0, 106.3 +- 14.9, 117.0 +- 18.6, and 134.1 +- 16.4 muM, respectively. Camphor beta-secretase 1 Homo sapiens