Title : Sildenafil-associated hepatoxicity: a review of the literature.

Pub. Date : 2017 Mar

PMID : 28379598






1 Functional Relationships(s)
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1 It is a selective phosphodiesterase type 5-enzyme inhibitor able to potentiate the downstream effects of nitric oxide on smooth muscle relaxation and vasodilation through its effects on the cyclic guanosine monophosphate (c-GMP) pathway in the erectile tissue of the penis. Nitric Oxide phosphodiesterase 5A Homo sapiens