Title : Connexin43 intercellular communication drives the early differentiation of human bone marrow stromal cells into osteoblasts.

Pub. Date : 2018 Feb

PMID : 28369869






1 Functional Relationships(s)
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1 Two independent procedures to reduce GJIC, a pharmacological approach with GJIC inhibitors (18alpha-glycyrrhetinic acid and Gap27 peptide) and a molecular approach using small interfering RNA against Cx43, demonstrated that the presence of Cx43 and functional junctional channels are essential to the ability of hBMSCs to differentiate into osteoblasts in vitro. 18alpha-glycyrrhetinic acid gap junction protein alpha 1 Homo sapiens